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PNPLA2 influences secretion of triglyceride-rich lipoproteins by human hepatoma cells

Patatin-like phospholipase domain-containing proteins (PNPLAs) are involved in triglyceride hydrolysis and lipid-droplet homeostasis in mice, but the physiological significance of the PNPLAs for triglyceride metabolism in human hepatocytes is unclear. Here, we investigate the roles of PNPLA2, PNPLA3...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Lipid Res
Hauptverfasser: Taxiarchis, Apostolos, Mahdessian, Hovsep, Silveira, Angela, Fisher, Rachel M., van’t Hooft, Ferdinand M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547638/
https://ncbi.nlm.nih.gov/pubmed/30918066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M090928
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