Toxoplasma gondii ROP18 inhibits human glioblastoma cell apoptosis through a mitochondrial pathway by targeting host cell P2X1

BACKGROUND: Apoptosis plays a critical role in the embryonic development, homeostasis of immune system and host defense against intracellular microbial pathogens. Infection by the obligate intracellular pathogen Toxoplasma gondii can both inhibit and induce host cell apoptosis; however, the parasiti...

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Библиографические подробности
Опубликовано в: :Parasit Vectors
Главные авторы: Zhou, Li-Juan, Chen, Min, Puthiyakunnon, Santhosh, He, Cheng, Xia, Jing, He, Cynthia Y., Deng, Sheng-Qun, Peng, Hong-Juan
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2019
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Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547611/
https://ncbi.nlm.nih.gov/pubmed/31164145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-019-3529-1
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