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The HRP3 PWWP domain recognizes the minor groove of double-stranded DNA and recruits HRP3 to chromatin

HDGF-related protein 3 (HRP3, also known as HDGFL3) belongs to the family of HDGF-related proteins (HRPs) and plays an essential role in hepatocellular carcinoma pathogenesis. All HRPs have a PWWP domain at the N-terminus that binds both histone and DNA substrates. Despite previous advances in PWWP...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Tian, Wei, Yan, Peiqiang, Xu, Ning, Chakravorty, Arghya, Liefke, Robert, Xi, Qiaoran, Wang, Zhanxin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547440/
https://ncbi.nlm.nih.gov/pubmed/31162607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz294
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