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In vitro pharmacokinetic cell culture system that simulates physiologic nanoparticle exposure to macrophages

PURPOSE: An in vitro dynamic pharmacokinetic (PK) cell culture system was developed to more precisely simulate physiologic nanoparticle/drug exposure. METHODS: A dynamic PK cell culture system was developed to more closely reflect physiologic nanoparticle/drug concentrations that are changing with t...

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Publicat a:Pharm Res
Autors principals: Kutscher, Hilliard L., Morse, Gene D., Prasad, Paras N., Reynolds, Jessica L.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547366/
https://ncbi.nlm.nih.gov/pubmed/30710170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-019-2576-9
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