Development of a PD-L1-Expressing Orthotopic Liver Cancer Model: Implications for Immunotherapy for Hepatocellular Carcinoma

BACKGROUND: Anti-programmed cell death-1(anti-PD1) treatment has shown promising antitumor efficacy in patients with advanced hepatocellular carcinoma (HCC). This study sought to explore the functional significance of programmed death ligand-1 (PD-L1) expression in tumor cells in the tumor microenvi...

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Publicado en:Liver Cancer
Autores principales: Ou, Da-Liang, Lin, Yu-Yang, Hsu, Chia-Lang, Lin, Yin-Yao, Chen, Chia-Wei, Yu, Jhang-Sian, Miaw, Shi-Chuen, Hsu, Ping-Ning, Cheng, Ann-Lii, Hsu, Chiun
Formato: Artigo
Lenguaje:Inglês
Publicado: S. Karger AG 2019
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Original Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547269/
https://ncbi.nlm.nih.gov/pubmed/31192153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000489318
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