High-Throughput Microfluidic 3D Cytotoxicity Assay for Cancer Immunotherapy (CACI-IMPACT Platform)

Adoptive cell transfer against solid tumors faces challenges to overcome tumor microenvironment (TME), which plays as a physical barrier and provides immuno-suppressive conditions. Classical cytotoxicity assays are widely used to measure killing ability of the engineered cytotoxic lymphocytes as the...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Park, Dohyun, Son, Kyungmin, Hwang, Yunchan, Ko, Jihoon, Lee, Younggyun, Doh, Junsang, Jeon, Noo Li
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546835/
https://ncbi.nlm.nih.gov/pubmed/31191524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01133
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