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Reduction in H3K4me patterns due to aberrant expression of methyltransferases and demethylases in renal cell carcinoma: prognostic and therapeutic implications

Renal cell carcinoma (RCC) is the leading cause among cancer-related deaths due to urological cancers, which results in response to combination of genetic and epigenetic factors. Histone methylations have been implicated in renal tumorigenesis but their clinical significance and underlying pathology...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kumar, Aman, Kumari, Niti, Sharma, Ujjawal, Ram, Sant, Singh, Shrawan Kumar, Kakkar, Nandita, Kaushal, Karanvir, Prasad, Rajendra
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546756/
https://ncbi.nlm.nih.gov/pubmed/31160694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44733-y
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