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Induction of Brain Arteriovenous Malformation through CRISPR/Cas9 Mediated Somatic Alk1 Gene Mutations in Adult Mice
Brain arteriovenous malformation (bAVM) is an important risk factor for intracranial hemorrhage. The pathogenesis of bAVM has not been fully understood. Animal models are important tools for dissecting bAVM pathogenesis and testing new therapies. We have developed several mouse bAVM models using gen...
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| Publié dans: | Transl Stroke Res |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6546562/ https://ncbi.nlm.nih.gov/pubmed/30511203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12975-018-0676-1 |
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