ERR1- and PGC1α-associated mitochondrial alterations correlate with pan-cancer disparity in African Americans

BACKGROUND: African American patients have higher cancer mortality rates and shorter survival times compared with European American patients. Despite a significant focus on socioeconomic factors, recent findings strongly argue the existence of biological factors driving this disparity. Most of these...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Piyarathna, Danthasinghe Waduge Badrajee, Balasubramanian, Akhila, Arnold, James M., Lloyd, Stacy M., Karanam, Balasubramanyam, Castro, Patricia, Ittmann, Michael M., Putluri, Nagireddy, Navone, Nora, Jones, Jeffrey A., Yu, Wendong, Sandulache, Vlad C., Sikora, Andrew G., Michailidis, George, Sreekumar, Arun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Clinical Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546480/
https://ncbi.nlm.nih.gov/pubmed/30920960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI127579
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