Heroin addiction engages negative emotional learning brain circuits in rats

Opioid use disorder is associated with the emergence of persistent negative emotional states during drug abstinence that drive compulsive drug taking and seeking. Functional magnetic resonance imaging (fMRI) in rats identified neurocircuits that were activated by stimuli that were previously paired...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Carmack, Stephanie A., Keeley, Robin J., Vendruscolo, Janaina C. M., Lowery-Gionta, Emily G., Lu, Hanbing, Koob, George F., Stein, Elliot A., Vendruscolo, Leandro F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Concise Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546476/
https://ncbi.nlm.nih.gov/pubmed/30913040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI125534
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