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Maternal Inheritance of a Recessive RBP4 Defect in Canine Congenital Eye Disease

Maternally skewed transmission of traits has been associated with genomic imprinting and oocyte-derived mRNA. We report canine congenital eye malformations, caused by an amino acid deletion (K12del) near the N terminus of retinol-binding protein (RBP4). The disease is only expressed when both dam an...

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Bibliografische gegevens
Gepubliceerd in:Cell Rep
Hoofdauteurs: Kaukonen, Maria, Woods, Sean, Ahonen, Saija, Lemberg, Seppo, Hellman, Maarit, Hytönen, Marjo K., Permi, Perttu, Glaser, Tom, Lohi, Hannes
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546432/
https://ncbi.nlm.nih.gov/pubmed/29847795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.04.118
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