Cross-cleavage activity of Cas6b in crRNA processing of two different CRISPR-Cas systems in Methanosarcina mazei Gö1

The clustered regularly interspaced short palindromic repeat (CRISPR) system is a prokaryotic adaptive defense system against foreign nucleic acids. In the methanoarchaeon Methanosarcina mazei Gö1, two types of CRISPR-Cas systems are present (type I-B and type III-C). Both loci encode a Cas6 endonuc...

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發表在:RNA Biol
Main Authors: Nickel, Lisa, Ulbricht, Andrea, Alkhnbashi, Omer S., Förstner, Konrad U., Cassidy, Liam, Weidenbach, Katrin, Backofen, Rolf, Schmitz, Ruth A.
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2018
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Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546354/
https://ncbi.nlm.nih.gov/pubmed/30153081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1514234
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