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Repeat modularity as a beneficial property of multiple CRISPR-Cas systems

CRISPR-Cas systems are a highly effective immune mechanism for prokaryotes, providing defense against invading foreign DNA. By definition, all CRISPR-Cas systems have short repeats interspersing their spacers. These repeats play a key role in preventing cleavage of self DNA and in the integration of...

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Bibliographic Details
Published in:RNA Biol
Main Authors: Yair, Yael, Gophna, Uri
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546348/
https://ncbi.nlm.nih.gov/pubmed/29923454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1474073
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