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Caspase-3 cleavage of Salmonella type III secreted effector protein SifA is required for localization of functional domains and bacterial dissemination

SifA is a bi-functional Type III Secretion System (T3SS) effector protein that plays an important role in Salmonella virulence. The N-terminal domain of SifA binds SifA-Kinesin-Interacting-Protein (SKIP), and via an interaction with kinesin, forms tubular membrane extensions called Sif filaments (Si...

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Bibliografiske detaljer
Udgivet i:Gut Microbes
Main Authors: Patel, Samir, Wall, Daniel M., Castillo, Antonio, McCormick, Beth A.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546311/
https://ncbi.nlm.nih.gov/pubmed/30727836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19490976.2018.1506668
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