Serum retinol concentrations demonstrate high specificity after correcting for inflammation but questionable sensitivity compared with liver stores calculated from isotope dilution in determining vitamin A deficiency in Thai and Zambian children

Background: The WHO estimates that 190 million preschool children have vitamin A deficiency (VAD). Serum retinol (SR) concentration is a common indicator of vitamin A (VA) status, but SR is homeostatically controlled and suppressed during inflammation, which may lead to misdiagnosis. Objective: The...

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Veröffentlicht in:Am J Clin Nutr
Hauptverfasser: Suri, Devika J, Tanumihardjo, Jacob P, Gannon, Bryan M, Pinkaew, Siwaporn, Kaliwile, Chisela, Chileshe, Justin, Tanumihardjo, Sherry A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
Schlagworte:
Original Research Communications
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546224/
https://ncbi.nlm.nih.gov/pubmed/26447158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/ajcn.115.113050
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