HIV disease progression: Overexpression of the ectoenzyme CD38 as a contributory factor?

Despite abundant evidence associating CD38 overexpression and CD4 T cell depletion in HIV infection, no causal relation has been investigated. To address this issue, we propose a series of mechanisms, supported by evidence from different fields, by which CD38 overexpression could facilitate CD4 T ce...

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Udgivet i:Bioessays
Main Authors: Rodríguez-Alba, J. C., Abrego-Peredo, A., Gallardo-Hernández, C., Pérez-Lara, J., Santiago-Cruz, J. W., Jiang, J., W., Espinosa, E.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545924/
https://ncbi.nlm.nih.gov/pubmed/30537007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201800128
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