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SOX9 activity is induced by oncogenic Kras to affect MDC1 and MCMs expression in pancreatic cancer
SRY (sex determining region Y)-box 9 (SOX9) is required for oncogenic Kras-mediated acinar-to-ductal metaplasia (ADM), pancreatic intraepithelial neoplasias (PanINs) and ultimately pancreatic ductal adenocarcinoma (PDAC). However, how oncogenic Kras affects SOX9 activity is not yet understood, and S...
Sparad:
| I publikationen: | Oncogene |
|---|---|
| Huvudupphovsmän: | , , , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2017
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6545484/ https://ncbi.nlm.nih.gov/pubmed/29059173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.393 |
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