Inhibiting Hydrogen Sulfide Production in Umbilical Stem Cells Reduces Their Protective Effects During Experimental Necrotizing Enterocolitis

INTRODUCTION: Umbilical mesenchymal stem cells (USC) have been shown to reduce illness in animal models of necrotizing enterocolitis (NEC), possibly through the paracrine release of hydrogen sulfide (H(2)S). We hypothesized that animals treated with USCs with inhibited H(2)S synthesis would exhibit...

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Veröffentlicht in:J Pediatr Surg
Hauptverfasser: Drucker, Natalie A., te Winkel, Jan P., Christopher Shelley, W., Olson, Kenneth R., Markel, Troy A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545254/
https://ncbi.nlm.nih.gov/pubmed/30879750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpedsurg.2019.02.037
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