Slow extension of the invading DNA strand in a D-loop formed by RecA-mediated homologous recombination may enhance recognition of DNA homology

DNA recombination resulting from RecA-mediated strand exchange aided by RecBCD proteins often enables accurate repair of DNA double-strand breaks. However, the process of recombinational repair between short DNA regions of accidental similarity can lead to fatal genomic rearrangements. Previous stud...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Lu, Daniel, Danilowicz, Claudia, Tashjian, Tommy F., Prévost, Chantal, Godoy, Veronica G., Prentiss, Mara
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2019
Subjects:
DNA and Chromosomes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544866/
https://ncbi.nlm.nih.gov/pubmed/30975899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007554
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