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Myxoma virus M013 protein antagonizes NF-κB and inflammasome pathways via distinct structural motifs
Among the repertoire of immunoregulatory proteins encoded by myxoma virus, M013 is a viral homologue of the viral pyrin domain-only protein (vPOP) family. In myeloid cells, M013 protein has been shown to inhibit both the inflammasome and NF-κB signaling pathways by direct binding to ASC1 and NF-κB1,...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6544859/ https://ncbi.nlm.nih.gov/pubmed/30940649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006040 |
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