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A promiscuous kinase inhibitor reveals secrets to cancer cell survival

Deregulated kinase signaling networks drive the growth and survival of many cancer cells. However, the genetic complexity and rapidly evolving nature of most cancer cells create challenges when identifying the most relevant kinases to inhibit to achieve optimal therapeutic benefits. A new strategy t...

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Vydáno v:J Biol Chem
Hlavní autor: Shapiro, Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544853/
https://ncbi.nlm.nih.gov/pubmed/31127063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.H119.009103
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