ロード中...
PtdIns3P phosphatases MTMR3 and MTMR4 negatively regulate innate immune responses to DNA through modulating STING trafficking
The innate immune system plays an essential role in initial recognition of pathogen infection by producing inflammatory cytokines and type I interferons. cGAS is a cytoplasmic sensor for DNA derived from DNA viruses. cGAS binding with DNA induces the production of cGAMP, a second messenger that asso...
保存先:
| 出版年: | J Biol Chem |
|---|---|
| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2019
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6544844/ https://ncbi.nlm.nih.gov/pubmed/30944173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005731 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|