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Yeast-secreted, dried and food-admixed monomeric IgA prevents gastrointestinal infection in a piglet model
A scalably manufacturable oral antibody technology that can interfere with gastrointestinal (GI) targets is needed. Contrary to the complex native secretory IgA, we achieve this using a single-gene encoded monomeric-IgA-like antibody, composed of camelid VHH fused to IgA Fc (mVHH-IgA). This can be p...
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| Publicat a: | Nat Biotechnol |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6544532/ https://ncbi.nlm.nih.gov/pubmed/30936561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-019-0070-x |
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