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Ring-Expansion Approaches for the Total Synthesis of Salimabromide

We describe the evolution of a synthetic strategy for the construction of the marine polyketide salimabromide. Combining a bicyclo[3.1.0]hexan-2-one ring-expansion to build up a functionalized naphthalene and an unprecedented rearrangement/cyclization cascade, enabled synthesis of a dearomatized tri...

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發表在:Tetrahedron
Main Authors: Schmid, Matthias, Grossmann, Adriana S., Mayer, Peter, Müller, Thomas, Magauer, Thomas
格式: Artigo
語言:Inglês
出版: 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544523/
https://ncbi.nlm.nih.gov/pubmed/31160829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2019.03.010
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