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HDAC5 promotes optic nerve regeneration by activating the mTOR pathway

Neurons in the central nervous system (CNS) regenerate poorly compared to their counterparts in the peripheral nervous system. We previously showed that, in peripheral sensory neurons, nuclear HDAC5 inhibits the expression of regenerative associated genes. After nerve injury, HDAC5 is exported to th...

詳細記述

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書誌詳細
出版年:Exp Neurol
主要な著者: Pita-Thomas, Wolfgang, Mahar, Marcus, Joshi, Avni, Gan, Di, Cavalli, Valeria
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544474/
https://ncbi.nlm.nih.gov/pubmed/30910408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2019.03.011
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