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HDAC5 promotes optic nerve regeneration by activating the mTOR pathway

Neurons in the central nervous system (CNS) regenerate poorly compared to their counterparts in the peripheral nervous system. We previously showed that, in peripheral sensory neurons, nuclear HDAC5 inhibits the expression of regenerative associated genes. After nerve injury, HDAC5 is exported to th...

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Vydáno v:Exp Neurol
Hlavní autoři: Pita-Thomas, Wolfgang, Mahar, Marcus, Joshi, Avni, Gan, Di, Cavalli, Valeria
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544474/
https://ncbi.nlm.nih.gov/pubmed/30910408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2019.03.011
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