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HDAC5 promotes optic nerve regeneration by activating the mTOR pathway

Neurons in the central nervous system (CNS) regenerate poorly compared to their counterparts in the peripheral nervous system. We previously showed that, in peripheral sensory neurons, nuclear HDAC5 inhibits the expression of regenerative associated genes. After nerve injury, HDAC5 is exported to th...

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Dades bibliogràfiques
Publicat a:Exp Neurol
Autors principals: Pita-Thomas, Wolfgang, Mahar, Marcus, Joshi, Avni, Gan, Di, Cavalli, Valeria
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544474/
https://ncbi.nlm.nih.gov/pubmed/30910408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2019.03.011
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