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HDAC5 promotes optic nerve regeneration by activating the mTOR pathway

Neurons in the central nervous system (CNS) regenerate poorly compared to their counterparts in the peripheral nervous system. We previously showed that, in peripheral sensory neurons, nuclear HDAC5 inhibits the expression of regenerative associated genes. After nerve injury, HDAC5 is exported to th...

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Bibliografische gegevens
Gepubliceerd in:Exp Neurol
Hoofdauteurs: Pita-Thomas, Wolfgang, Mahar, Marcus, Joshi, Avni, Gan, Di, Cavalli, Valeria
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544474/
https://ncbi.nlm.nih.gov/pubmed/30910408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2019.03.011
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