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Identification of EOMES-expressing spermatogonial stem cells and their regulation by PLZF

Long-term maintenance of spermatogenesis in mammals is supported by GDNF, an essential growth factor required for spermatogonial stem cell (SSC) self-renewal. Exploiting a transgenic GDNF overexpression model, which expands and normalizes the pool of undifferentiated spermatogonia between Plzf (+/+)...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Sharma, Manju, Srivastava, Anuj, Fairfield, Heather E, Bergstrom, David, Flynn, William F, Braun, Robert E
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544432/
https://ncbi.nlm.nih.gov/pubmed/31149899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.43352
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