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Efficacy of sonothrombolysis using microbubbles produced by a catheter-based microfluidic device in a rat model of ischemic stroke

Limitations of existing thrombolytic therapies for acute ischemic stroke have motivated the development of catheter-based approaches that utilize no or low doses of thrombolytic drugs combined with a mechanical action to either dissolve or extract the thrombus. Sonothrombolysis accelerates thrombus...

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Detalhes bibliográficos
Publicado no:Ann Biomed Eng
Main Authors: Dixon, Adam J, Li, Jun, Rickel, John-Marschner Robert, Klibanov, Alexander L., Zuo, Zhiyi, Hossack, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544382/
https://ncbi.nlm.nih.gov/pubmed/30689066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10439-019-02209-0
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