MicroRNA modulated networks of adaptive and innate immune response in pancreatic ductal adenocarcinoma

Despite progress in treatment strategies, only ~24% of pancreatic ductal adenocarcinoma (PDAC) patients survive >1 year. Our goal was to elucidate deregulated pathways modulated by microRNAs (miRNAs) in PDAC and Vater ampulla (AMP) cancers. Global miRNA expression was identified in 19 PDAC, 6 AMP...

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Pubblicato in:PLoS One
Autori principali: Felix, Tainara F., Lopez Lapa, Rainer M., de Carvalho, Márcio, Bertoni, Natália, Tokar, Tomas, Oliveira, Rogério A., M. Rodrigues, Maria A., Hasimoto, Cláudia N., Oliveira, Walmar K., Pelafsky, Leonardo, Spadella, César T., Llanos, Juan C., F. Silva, Giovanni, Lam, Wan L., Rogatto, Silvia Regina, Amorim, Luciana Schultz, Drigo, Sandra A., Carvalho, Robson F., Reis, Patricia P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544344/
https://ncbi.nlm.nih.gov/pubmed/31150430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0217421
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