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Developmental Apoptosis Promotes a Disease-Related Gene Signature and Independence from CSF1R Signaling in Retinal Microglia

Microglia have important remodeling functions in neurodevelopment, aging, and disease, with evidence for molecular diversity. However, the signaling pathways and environmental cues that drive diverse states of microglia are incompletely understood. We profiled microglia of a discrete developing CNS...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Anderson, Sarah R., Roberts, Jacqueline M., Zhang, Jianmin, Steele, Michael R., Romero, Cesar O., Bosco, Alejandra, Vetter, Monica L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544177/
https://ncbi.nlm.nih.gov/pubmed/31091440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.04.062
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