Genetic and Functional Dissection of the Role of Individual 5-HT(2) Receptors as Entry Receptors for JC Polyomavirus

JC polyomavirus (JCPyV) is a ubiquitous human pathogen that causes progressive multifocal leukoencephalopathy (PML). The entry receptors for JCPyV belong to the 5-hydroxytryptamine 2 receptor (5-HT(2)R) family, but how individual members of the family function to facilitate infection is not known. W...

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Pubblicato in:Cell Rep
Autori principali: Assetta, Benedetta, Morris-Love, Jenna, Gee, Gretchen V., Atkinson, Abigail L., O’Hara, Bethany A., Maginnis, Melissa S., Haley, Sheila A., Atwood, Walter J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544161/
https://ncbi.nlm.nih.gov/pubmed/31091436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.04.067
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