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Low-grade inflammation aggravates rotenone neurotoxicity and disrupts circadian clock gene expression in rats

A single injection of LPS produced low-grade neuroinflammation leading to Parkinson’s disease (PD) in mice several months later. Whether such a phenomenon occurs in rats and whether such low-grade neuroinflammation would aggravate rotenone (ROT) neurotoxicity and disrupts circadian clock gene/protei...

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Bibliographic Details
Published in:Neurotox Res
Main Authors: Li, Huan, Song, Sheng, Wang, Yuan, Huang, Chun, Zhang, Feng, Liu, Jie, Hong, Jau-Shyong
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6543539/
https://ncbi.nlm.nih.gov/pubmed/30328585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12640-018-9968-1
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