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Pentamidine Inhibits Titanium Particle-Induced Osteolysis In Vivo and Receptor Activator of Nuclear Factor-κB Ligand-Mediated Osteoclast Differentiation In Vitro

BACKGROUND: Wear debris-induced osteolysis leads to periprosthetic loosening and subsequent prosthetic failure. Since excessive osteoclast formation is closely implicated in periprosthetic osteolysis, identification of agents to suppress osteoclast formation and/or function is crucial for the treatm...

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Detalhes bibliográficos
Publicado no:Tissue Eng Regen Med
Main Authors: Ihn, Hye Jung, Kim, Kiryeong, Cho, Hye-Sung, Park, Eui Kyun
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Singapore 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542890/
https://ncbi.nlm.nih.gov/pubmed/31205855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13770-019-00186-y
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