Potential resistant mutations within HBV reverse transcriptase sequences in nucleos(t)ide analogues-experienced patients with hepatitis B virus infection

This study was performed to analyze the potential resistant mutations within HBV reverse transcriptase (RT) sequences against nucleos(t)ide analogues (NA). HBV DNA RT region spanning from amino acid 169 to 250 was amplified and sequenced from 435 HBV patients who experienced NA treatment. Among stud...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Xiaoman, Chen, Xianli, Wei, Meijuan, Zhang, Chunyu, Xu, Tao, Liu, Liguan, Xu, Zhengju
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542804/
https://ncbi.nlm.nih.gov/pubmed/31147594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44604-6
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