Coordinating Tissue Regeneration through TGF-β Activated Kinase 1 (TAK1) In-activation and Re-activation

Aberrant wound healing presents as inappropriate or insufficient tissue formation. Using a model of musculoskeletal injury, we demonstrate that loss of TGF-β activated kinase 1 (TAK1) signaling reduces inappropriate tissue formation (heterotopic ossification) through reduced cellular differentiation...

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Publicado en:Stem Cells
Main Authors: Hsieh, Hsiao Hsin Sung, Agarwal, Shailesh, Cholok, David J., Loder, Shawn J., Kaneko, Kieko, Huber, Amanda, Chung, Michael T., Ranganathan, Kavitha, Habbouche, Joe, Li, John, Butts, Jonathan, Reimer, Jonathan, Kaura, Arminder, Drake, James, Breuler, Christopher, Priest, Caitlin R., Nguyen, Joe, Brownley, Cameron, Peterson, Jonathan, Ozgurel, Serra Ucer, Niknafs, Yashar S., Li, Shuli, Inagaki, Maiko, Scott, Greg, Krebsbach, Paul, Longaker, Michael T., Westover, Kenneth, Gray, Nathanael, Jun-Ninomiya-Tsuji, Mishina, Yuji, Levi, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542699/
https://ncbi.nlm.nih.gov/pubmed/30786091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2991
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