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Bmal1 deletion in mice facilitates adaptation to disrupted light/dark conditions

Recently, by using conventional and tamoxifen-inducible brain and muscle Arnt-like protein 1–knockout (Bmal1-KO) mice, we found that delaying the loss of circadian rhythms to adulthood attenuates the impact on general integrity and survival at least under 12-hour light/12-hour dark conditions. To un...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Yang, Guangrui, Chen, Lihong, Zhang, Jiayang, Ren, Baoyin, FitzGerald, Garret A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542608/
https://ncbi.nlm.nih.gov/pubmed/30973828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.125133
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