Biomarkers of endothelial activation/dysfunction distinguish subgroups of Ugandan patients with sepsis and differing mortality risks

BACKGROUND: Sepsis is a complex clinical syndrome with substantial heterogeneity. We sought to identify patterns of serum biomarkers of endothelial activation and dysfunction in individuals with sepsis and evaluate subgroup-specific differences in mortality. METHODS: Adult patients with sepsis (n =...

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Udgivet i:JCI Insight
Main Authors: Clark, Danielle V., Banura, Patrick, Bandeen-Roche, Karen, Liles, W. Conrad, Kain, Kevin C., Scheld, W. Michael, Moss, William J., Jacob, Shevin T.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2019
Fag:
Clinical Medicine
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542598/
https://ncbi.nlm.nih.gov/pubmed/31013257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.127623
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