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Unique mutation patterns in anaplastic thyroid cancer identified by comprehensive genomic profiling

INTRODUCTION: Anaplastic thyroid cancer (ATC) is a highly aggressive thyroid cancer. Those ATC with genomic alterations (GAs) in TSC2, ALK, and BRAF may respond to targeted therapies. METHODS: Comprehensive genomic profiling on 90 ATC specimens identified base substitutions, short insertions and del...

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Detalhes bibliográficos
Publicado no:Head Neck
Main Authors: Khan, Saad A., Ci, Bo, Xie, Yang, Gerber, David E., Beg, Muhammad S., Sherman, Steven I., Cabanillas, Maria E., Busaidy, Naifa L., Burtness, Barbara A., Heilmann, Andreas M., Bailey, Mark, Ross, Jeffrey S., Sher, David J., Ali, Siraj M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542589/
https://ncbi.nlm.nih.gov/pubmed/30758123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hed.25634
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