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C–H Functionalization of Amines via Alkene-Derived Nucleophiles through Cooperative Action of Chiral and Achiral Lewis Acid Catalysts: Applications in Enantioselective Synthesis

Catalytic transformations of α-amino C–H bonds to afford valuable enantiomerically enriched α-substituted amines, entities that are prevalent in pharmaceuticals and bioactive natural products, have been developed. Typically, such processes are carried out under oxidative conditions, and require prec...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Shang, Ming, Chan, Jessica Z., Cao, Min, Chang, Yejin, Wang, Qifan, Cook, Brennan, Torker, Sebastian, Wasa, Masayuki
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542567/
https://ncbi.nlm.nih.gov/pubmed/30045617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b06699
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