The THO complex coordinates transcripts for synapse development and dopamine neuron survival

Synaptic vesicle and active zone proteins are required for synaptogenesis. The molecular mechanisms for coordinated synthesis of these proteins are not understood. Using forward genetic screens, we identified the conserved THO nuclear export Complex (THOC) as an important regulator of presynapse dev...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Maeder, Celine I., Kim, Jae-Ick, Liang, Xing, Kaganovsky, Konstantin, Shen, Ao, Li, Qin, Li, Zhaoyu, Wang, Sui, Xu, X.Z. Shawn, Li, Jin Billy, Xiang, Yang Kevin, Ding, Jun B., Shen, Kang
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542560/
https://ncbi.nlm.nih.gov/pubmed/30146163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.07.046
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