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Specific In Situ Hepatitis B Viral Double Mutation (HBVDM) Detection in Urine with 60 copies/ml Analytical Sensitivity in a background of 250-fold Wild Type without DNA Isolation and Amplification
We have examined in situ detection of hepatitis B virus 1762T/1764A double mutation (HBVDM) in urine using a (Pb(Mg(1/3)Nb(2/3))O(3))(0.65)(PbTiO(3))(0.35) (PMN-PT) piezoelectric plate sensor (PEPS) coated with a 16-nucleotide (nt) probe DNA (pDNA) complementary to the HBVDM. The in situ mutation (M...
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| Publicado en: | Analyst |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6542474/ https://ncbi.nlm.nih.gov/pubmed/25599103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4an01885k |
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