Ferroptosis inhibitor alleviates Radiation-induced lung fibrosis (RILF) via down-regulation of TGF-β1

BACKGROUND: Radiation-induced lung fibrosis (RILF) is a severe and life-threatening complication of thoracic radiotherapy. Cell death is the key issue in RILF. Ferroptosis is a form programmed cell death implicated in the pathologies of inflammation. This study aimed to investigate the role of ferro...

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Bibliografiske detaljer
Udgivet i:J Inflamm (Lond)
Main Authors: Li, Xuan, Duan, Lijie, Yuan, Sujuan, Zhuang, Xibing, Qiao, Tiankui, He, Jian
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542066/
https://ncbi.nlm.nih.gov/pubmed/31160885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12950-019-0216-0
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