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Sepsis and septic shock: endothelial molecular pathogenesis associated with vascular microthrombotic disease

In addition to protective “immune response”, sepsis is characterized by destructive “endothelial response” of the host, leading to endotheliopathy and its molecular dysfunction. Complement activation generates membrane attack complex (MAC). MAC causes channel formation to the cell membrane of pathog...

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Bibliografische gegevens
Gepubliceerd in:Thromb J
Hoofdauteur: Chang, Jae C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542012/
https://ncbi.nlm.nih.gov/pubmed/31160889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12959-019-0198-4
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