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Genome-wide analysis of DNA replication timing in single cells: Yes! We’re all individuals

Recent studies have accomplished the extraordinary feat of measuring the exact status of DNA replication in individual cells. We outline how these studies have revealed surprising uniformity in how cells replicate their DNA, and consider the implications of this remarkable technological advance.

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Bibliographic Details
Published in:Genome Biol
Main Authors: Donaldson, Anne D., Nieduszynski, Conrad A.
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6541995/
https://ncbi.nlm.nih.gov/pubmed/31146781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1719-y
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