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Homozygous missense mutation Arg207Cys in the WEE2 gene causes female infertility and fertilization failure

PURPOSE: To investigate a novel mutation in the WEE2 gene in a female patient with primary infertility and fertilization failure. METHODS: Sanger sequencing was used to detect mutations in WEE2. The pathogenicity of the identified variant and its possible effects on the WEE2 protein were evaluated w...

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Dades bibliogràfiques
Publicat a:J Assist Reprod Genet
Autors principals: Yang, Xiaoyu, Shu, Li, Cai, Lingbo, Sun, Xueping, Cui, Yugui, Liu, Jiayin
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6541719/
https://ncbi.nlm.nih.gov/pubmed/30826994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-019-01418-9
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