Therapeutic benefit of combining calorie-restricted ketogenic diet and glutamine targeting in late-stage experimental glioblastoma

Glioblastoma (GBM) is an aggressive primary human brain tumour that has resisted effective therapy for decades. Although glucose and glutamine are the major fuels that drive GBM growth and invasion, few studies have targeted these fuels for therapeutic management. The glutamine antagonist, 6-diazo-5...

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Publicado en:Commun Biol
Main Authors: Mukherjee, Purna, Augur, Zachary M., Li, Mingyi, Hill, Collin, Greenwood, Bennett, Domin, Marek A., Kondakci, Gramoz, Narain, Niven R., Kiebish, Michael A., Bronson, Roderick T., Arismendi-Morillo, Gabriel, Chinopoulos, Christos, Seyfried, Thomas N.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6541653/
https://ncbi.nlm.nih.gov/pubmed/31149644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0455-x
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