Atypical function of a centrosomal module in WNT signalling drives contextual cancer cell motility

Centrosomes control cell motility, polarity and migration that is thought to be mediated by their microtubule-organizing capacity. Here we demonstrate that WNT signalling drives a distinct form of non-directional cell motility that requires a key centrosome module, but not microtubules or centrosome...

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Publicat a:Nat Commun
Autors principals: Luo, Yi, Barrios-Rodiles, Miriam, Gupta, Gagan D., Zhang, Ying Y., Ogunjimi, Abiodun A., Bashkurov, Mikhail, Tkach, Johnny M., Underhill, Ainsley Q., Zhang, Liang, Bourmoum, Mohamed, Wrana, Jeffrey L., Pelletier, Laurence
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6541620/
https://ncbi.nlm.nih.gov/pubmed/31142743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10241-w
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