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Using DNA Methylation to Validate an Electronic Medical Record Phenotype for Smoking

A validated, scalable approach to characterizing (phenotyping) smoking status is needed to facilitate genetic discovery. Using established DNA methylation sites from blood samples as a criterion standard for smoking behavior, we compare three candidate electronic medical record (EMR) smoking metrics...

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Bibliografiske detaljer
Udgivet i:Addict Biol
Main Authors: McGinnis, Kathleen A., Justice, Amy C., Tate, Janet P., Kranzler, Henry R., Tindle, Hilary A., Becker, William C., Concato, John, Gelernter, Joel, Li, Boyang, Zhang, Xinyu, Zhao, Hongyu, Crothers, Kristina, Xu, Ke
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6541538/
https://ncbi.nlm.nih.gov/pubmed/30284751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12670
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