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Cellular labeling of endogenous retrovirus replication (CLEVR) reveals de novo insertions of the gypsy retrotransposable element in cell culture and in both neurons and glial cells of aging fruit flies

Evidence is rapidly mounting that transposable element (TE) expression and replication may impact biology more widely than previously thought. This includes potential effects on normal physiology of somatic tissues and dysfunctional impacts in diseases associated with aging, such as cancer and neuro...

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Détails bibliographiques
Publié dans:PLoS Biol
Auteurs principaux: Chang, Yung-Heng, Keegan, Richard M., Prazak, Lisa, Dubnau, Josh
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6541305/
https://ncbi.nlm.nih.gov/pubmed/31095565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000278
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