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The role of B cells in multiple sclerosis: current and future therapies

While it was long held that T cells were the primary mediators of multiple sclerosis (MS) pathogenesis, the beneficial effects observed in response to treatment with Rituximab, a monoclonal antibody (mAb) targeting CD20, shed light on a key contributor to MS that had been previously underappreciated...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Immunol
Hauptverfasser: Negron, Austin, Robinson, Rachel R., Stuve, Olaf, Forsthuber, Thomas G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6540809/
https://ncbi.nlm.nih.gov/pubmed/31130183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2018.10.006
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