Pressure overload induced right ventricular remodeling is not attenuated by the anti-fibrotic agent pirfenidone

Cardiac fibrosis contributes to the development of heart failure in pulmonary hypertension. We aimed to assess the development of fibrosis and the effects of treatment with the anti-fibrotic agent pirfenidone in pressure overload induced right ventricular (RV) failure. Wistar rat weanlings were rand...

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Detalhes bibliográficos
Publicado no:Pulm Circ
Main Authors: Andersen, Stine, Birkmose Axelsen, Julie, Ringgaard, Steffen, Randel Nyengaard, Jens, Holm Nielsen, Signe, Genovese, Federica, Asser Karsdal, Morten, Adler Hyldebrandt, Janus, Brandt Sørensen, Charlotte, de Man, Frances S., Jan Bogaard, Harm, Erik Nielsen-Kudsk, Jens, Andersen, Asger
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6540527/
https://ncbi.nlm.nih.gov/pubmed/30997866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045894019848659
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